Tsopano tachita bwino jekeseni wa plasma wolemera wa platelet (PRP) ndi hyaluronic acid wa bondo la OA ndipo ambiri akhala ndi matenda apamwamba kwambiri kuposa oyenera (oyankha bwino kwambiri amakhala ndi kusintha kochepa kwambiri kwa radiological), koma ~ 80% akhala ndi nthawi yayitali komanso mayankho abwino ku PRP kapena viscosupplementation kuposa mankhwala am'mbuyomu a intra-articulator corticosteroid.
Ndemanga imodzi yaposachedwa ndi kuyesa kwaposachedwa kwandipangitsa kuti ndisinthe mwachidule pa PRP ndi viscosupplementation therapy ya mawondo.
Ndemanga ya Arthroscopy inamaliza PRP "ndi chithandizo chotheka kwa mawondo OA ndipo ali ndi kuthekera kotsogolera ku mpumulo wa zizindikiro kwa miyezi 12".Komanso intra-articular PRP therapy "imapereka chithandizo chabwino kwa odwala omwe ali ndi kusintha kwa mawondo oyambirira, ndipo kugwiritsidwa ntchito kwake kuyenera kuganiziridwa kwa odwala omwe ali ndi mawondo OA" . .
Mapangidwe Oyesa:
•Odwala a 162 omwe ali ndi magawo osiyanasiyana a mawondo OA adagawidwa mwachisawawa m'magulu anayi: aliyense anali ndi jekeseni wa 3 aliyense: 3 IA mlingo wa PRP, mlingo umodzi wa PRP, 3 inj wa HA (hyaluronic acid) kapena jekeseni wa saline (control) .
•Timagulu ting'onoting'ono tiwiri: OA oyambirira (Kellgren-Lawrence giredi 0 yokhala ndi chichereŵechereŵe chochepa kapena giredi I-III) ndi OA yapamwamba (Kellgren-Lawrence giredi IV).
•Odwalawo adayesedwa asanabadwe jekeseni komanso pakutsata kwa miyezi ya 6 pogwiritsa ntchito EuroQol visual analogue scale (EQ-VAS) ndi International Knee Documentation Committee (IKDC) subjective scores.
Zotsatira:
•Panali kusintha kwakukulu kwa chiwerengero cha IKDC ndi EQ-VAS m'magulu onse ochiritsira poyerekeza ndi gulu lolamulira.
•Mawondo a odwala omwe amathandizidwa ndi majekeseni atatu a PRP anali abwino kwambiri kuposa odwala omwe ali m'magulu ena.Panalibe kusiyana kwakukulu pakati pa odwala ambiri omwe anabayidwa ndi mlingo umodzi wa PRP kapena HA.
• M'magulu oyambirira a OA, zotsatira zabwino kwambiri zachipatala zinapezedwa kwa odwala omwe amathandizidwa ndi majekeseni atatu a PRP, koma panalibe kusiyana kwakukulu mu zotsatira zachipatala za odwala omwe ali ndi OA yapamwamba pakati pa magulu ochiritsira.
Mapeto:
1.Zotsatira zachipatala za phunziroli zikuwonetsa chithandizo cha intra-articular PRP ndi HA pamagawo onse a mawondo OA.
2.Kwa odwala omwe ali ndi OA yoyambirira, jakisoni wa PRP angapo (3) ndiwothandiza kuti apeze zotsatira zabwino zachipatala.
3.Kwa odwala omwe ali ndi OA yapamwamba, jakisoni wambiri sasintha kwambiri zotsatira za odwala pagulu lililonse.
Nthawi yotumiza: Nov-07-2022