Kuchokera pakubwera kwa njira zakulera zapakamwa zachikazi mu 1950s mpaka kubadwa kwa test tube mwana mu 1970s komanso kupanga bwino kwa nkhosa za Dolly kumapeto kwa zaka za m'ma 1990, ukadaulo wamankhwala obereketsa wapanga kupambana kwakukulu kwaukadaulo wothandizidwa ndi Human assisted reproductive technology (Art) makamaka ndiukadaulo wapadera. kuthandiza odwala amene akadali sangathe kutenga pakati pambuyo wokhazikika mankhwala kuti yokumba kuphatikiza mazira ndi umuna pansi zasayansi zinthu kukwaniritsa mimba.Pamene teknolojiyi imalekanitsa kwathunthu kugonana ndi kubereka, chitukuko chake chofulumira chabweretsanso mndandanda wa zovuta zamakhalidwe, zamalamulo ndi zamagulu, zomwe zimapangitsa kuti chitukuko cha zojambulajambula chikhale chosiyana kwambiri ndi maphunziro ena azachipatala, kukhala mankhwala omwe akukula mkangano.
Kusabereka ndi matenda obwera chifukwa cholephera kutenga pathupi pakatha miyezi 12 kapena kuposerapo mukugonana mosalekeza popanda kulera.Kuchuluka kwa anthu osabereka padziko lonse lapansi kwawonjezeka kuchoka pa 11% mu 1997 kufika pa 15.4% mu 2018, ndipo akuyembekezeka kuwonjezeka kufika pa 17.2% mu 2023. 2023, pomwe kuchuluka kwa kusabereka ku China kukuyembekezeka kukwera kuchoka pa 16.0% mu 2018 mpaka 18.2% mu 2023.
